Joystick play may be rough, I have configed a gamepad(previously discribed) with walking and jumping commands, as well as "Tab" to target, and auto attack, but now I got both hands on this thing and cant do jack without letting go and clicking with a mouse. I did this for a epelitic who has some nerological dammage from his sugery. and it didnt work so well, we re arranged and got a game pad with more buttons, and that worked, for some stuff, but he was still limited to 4-5 actions on the game pad. One poster here on the alla pages referd to a N52, and I ended up getting one for myself, and showed it to my buddie(whos left sidedammaged and his arma and hand rest close to his right leg, he is able to set the N52(part keyboard/part amepad) on his right leg and with a mouse can get arround as fast as anybody else, just takes some time to cast as he has to click everything(he still is a amazing healer).
P.S. their is a add for the N52 in the link above me.