I create multiple windows. Then filter text to each one for different things.
Window1, stretched across the bottom just above the letterbox bar. I 50% transparent it, fully opaque text, limit it to Chat, NPC text, game text, con, etc.
Below that in a smaller box, I have it filtered to Player Tells, and Customer Service (GM tells).
To the right of the personal tells box, I have one of the same size for channel chats I belong to. to the left of the personal tells box, I have my spells text window, it shows spell text, non-melee damage, heroic oppurtunities, etc.
Above that stretched virtically, I have my Ability bar and next to that I have my alt ability bar.
Above those I have a block window dedicated to battle damage etc...
I will take a screenshot and post a link to it later so you can get a better idea of what I mean.